Science behind Lion’s Mane Mushroom (Hericium erinaceus) properties for human health

28.02.2023

542 words | 3 min reading time
ArticlesMedicinal mushroomsNatural medicine
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Table of Contents

What is Lion’s Mane Mushroom?

Lion’s Mane Mushroom (Hericium erinaceus) is a unique, shaggy-looking fungus that resembles the mane of a lion. Traditionally used in Chinese medicine for centuries, it’s now gaining popularity in the West for its impressive range of potential health benefits — from brain support to gut health.

You can find Lion’s Mane in powdered supplements, tinctures, capsules, and even fresh in specialty markets.

Bioactive Compounds and Their Effects

Lion’s Mane contains several powerful compounds that are responsible for its medicinal properties:

Polysaccharides – known for immune-boosting and anti-inflammatory properties

Hericenones – stimulate nerve growth factor (NGF) production in the brain

Erinacines – penetrate the blood-brain barrier and promote neurogenesis

Together, these compounds may help protect neurons, reduce oxidative stress, and support regeneration of nerve tissue.

🧪 See related study on neuroregenerative effects: PubMed Source

Lion’s Mane and Cognitive Health

One of the most studied benefits of Lion’s Mane is its impact on cognitive function.

Potential cognitive benefits include:

  • Improved memory and recall
  • Enhanced focus and concentration
  • Protection against age-related cognitive decline

In clinical trials, daily supplementation with Lion’s Mane extract improved cognitive performance in adults with mild cognitive impairment within 8–12 weeks【source: PubMed】.

Benefits for Heart and Circulation

Lion’s Mane may also support cardiovascular health by:

  • Lowering LDL (bad) cholesterol levels
  • Improving blood flow
  • Reducing systemic inflammation

These effects are attributed to its antioxidant properties, which help reduce oxidative stress and support vascular function.

Want to explore more cardiovascular-supporting mushrooms? Check out our Cordyceps guide.

Digestive and Gut Health Support

Studies have also shown that Lion’s Mane can help restore balance in the digestive system.

Benefits for digestive health include:

  • Reducing inflammation in the gut lining
  • Supporting beneficial gut microbiota
  • Alleviating symptoms of IBS (Irritable Bowel Syndrome)

Its prebiotic effect promotes the growth of healthy bacteria, making it a great functional supplement for anyone with gut sensitivities.

How to Use Lion’s Mane Mushroom

Lion’s Mane is available in various forms:

  • Powdered extract (great in coffee or smoothies)
  • Capsules (for easy daily dosage)
  • Tinctures (for fast absorption)
  • Cooked fresh (when available)

Recommended dosage:
For cognitive and gut support, studies suggest 500–3000 mg of Lion’s Mane extract daily, depending on concentration and extract ratio (typically 8:1 or 10:1).

Always consult a healthcare professional before adding new supplements to your routine.

Final Thoughts

Lion’s Mane mushroom is a fascinating functional food with a growing body of evidence supporting its:

Neuroprotective effects

Cognitive-enhancing properties

Anti-inflammatory and gut-supportive actions

Whether you’re seeking mental clarity, digestive balance, or long-term brain support, Lion’s Mane is one of nature’s most powerful allies.

Further Reading & Sources
Lion’s Mane and NGF – NIH

Traditional Chinese Medicine Uses

Mushroom-Guide Series: Lion’s Mane vs Cordyceps
Interested in trying Lion’s Mane?

Check out our curated Lion’s Mane supplements guide or explore the Shop for trusted brands.


Kamila

By Kamila – Strongly believes that humans deserve healthier and more sustainable food and drinks. Fascinated with functional fungi and plants. Has a background in the NGO sector, where she learned how to connect purpose with action. A year-round cyclist who leaves stress on the yoga mat.

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